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doi: 10.3389/fimmu.2025.1530301 Received 18 November 2024 Accepted 31 March 2025 Published 16 May 2025 Volume 16 - 2025 Edited by Sudhir Gupta, University of California, Irvine, United States Reviewed by Hridesh Banerjee, University of Pittsburgh, United States Gul Ahmad, Peru State College, United States Updates Copyright 2025 Shi, Yu, Xie, Yin, Chen, Zhao and Zhao

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Pathogen-associated molecular patterns such as LPS, induce neutrophils to release NETs by activating toll-like receptor 4 (TLR4)