l carnitine for heart failure Essential L-Carnitine L-Carnitine | Linus Pauling Institute
Description
Using both an MCAO/R rat models and an in vitro OGD/R cell models (136,137), researchers found that TSA inhibited the expression of pro-inflammatory cytokines (IL-1, IL-6 and TNF-), reduced levels of pro-apoptotic proteins (Bax and Cleaved-Caspase-3) and enhanced the expression of the anti-apoptotic protein Bcl-2
The studys authors emphasize the need for further clinical trials to validate these initial findings
It reduces contact of inflammatory proteins with the intestinal mucosa, thereby enhancing recovery from intestinal barrier compromise and inflammation
Chechic et al
