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Figure 6 Figure 7 4 Discussion The relevance of innate immune pathways in melanoma treatment is highlighted by some immunotherapy approaches such as TLR7 in the adjuvant therapy with imiquimod (36), TLR9 in the development of the emerging agonists tilsotolimod and vidutolimod (37), STING in the case of ADU S-100 (38), and the clinical use of IFN- (39)

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10.1210/endo.138.10.5453 Endocrinology 130 VillaE.MarchettiS.RicciJ

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Glutathione, Accessed April 4, 2021 Leukotrienes, Accessed April 4, 2021 Melanin (Compound), Accessed April 4, 2021 Skin lightening, Accessed April 4, 2021 Melanin, Accessed April 4, 2021 Intravenous glutathione for skin lightening: inadequate safety data, Accessed April 4, 2021 Glutathione as a skin whitening agent: Facts, myths, evidence and controversies, Accessed April 4, 2021 The role of systemic treatments for skin lightening, Accessed April 4, 2021 Current Version 09/01/2022 Written by Louise Nichole Logarta Medically reviewed by Angeli Eloise E

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