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In idiopathic pulmonary fibrosis models, Zhang et al
Here we defined a signature of 59 genes and two metabolites (GSH and NADP) that is robustly associated with NRF2 dependency across an extensive panel of cancer cell lines
QSSA was used in this iteration of the design to assume enzyme levels stayed constant, but further investigation of the induction of oxidative stress genes by ROS and how this might change enzyme concentrations would be of value
L-Cysteine has a unique ability to influence the metabolic pathway of melanin production
