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From mild rashes to rare vascular problems, there are things to watch out for

As many as 75 percent of patients lost at least 10 percent of their body weight at week 36

However, it is noteworthy that knockdown of NNMT does not seem to affect NAD + levels in the liver, indicating potential divergent regulatory mechanisms of NNMT in these tissues and suggesting the existence of redundant pathways in NAD + metabolism regulation (Trammell and Brenner, 2015)