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Philosophical transactions of the Royal Society B in Biological Sciences

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Sensing of DNA damage by XPC/Rad4: one protein for many lesions

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Hydrogen peroxide can also be generated by the 2-electron reduction of oxygen by various oxidoreductases, including xanthine oxidase, which, recent findings suggest, predominately produces hydrogen peroxide (33, 195)

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these enzymes are the most important constituent of the oxidative machinery, together with the endoplasmic reticulum thiol oxidase (ERO1) [52]

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