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doi: 10.1097/00005072-199709000-00002 26 PloweyEDBussiereTRajagovindanRSebaluskyJHamannSvon HehnCet al
Dual agonists like tirzepatide slow gastric emptying because of their GLP-1 activity, not their GIP activity
Second, it is a gastric effect achieved through the brain , via vagal outflow to the stomach, not through amylin acting locally on gastric tissue
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