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Adverse effects of arecoline and nicotine on human periodontal ligament fibroblasts in vitro

It also enhances the activity of detoxification enzymes, such as glutathione S-transferases (GSTs), which conjugate toxins to Glutathione, facilitating their elimination (Lu, 2013)

A study investigated the possible pathway by which H 2 O 2 induced apoptosis in glioma cells and concluded that oxidative stress inhibited glioma cell growth and induced apoptosis via a caspase-3-dependent pathway (Liu et al., 2015)

A decrease in glutathione levels can lead to a decrease in methylation, which can have serious implications for cellular health and function