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Additionally, it decreased the expression and movement of VEGFR-2 in HUVECs.53 Luteolin Luteolin, a flavonoid, exhibited significant cytotoxicity against both HCT116 and MDA-MB231 cell lines

Safety observations were similar between the treatment arms, with most adverse events being mild to moderate in severity [34]

Researcher Loren Pickart, PhD, who first isolated GHK from human plasma, described it as having a "profound effect on the reset of human genes toward a more youthful state." More recent genomic analyses confirm that GHK-Cu shifts gene expression patterns in aging tissue toward patterns characteristic of much younger tissue effectively acting as a biological reset at the cellular level