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More important than the dosage is consistency
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Fluvoxamine also has been reported to decrease the metabolic clearance of some benzodiazepines, including alprazolam, which is metabolized primarily by CYP-3A4, and diazepam, which is substrate for both CYP-2C19 and CYP-3A4
This metal bound A 142 has been investigated as a cause of ROS as copper and iron bound to these plaques are redox active and can participate in the Fenton reaction to generate ROS (Sasanian et al., 2020)
