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Current investigations have deepened our understanding of the interplay between nutrients and epigenetic regulation, illustrating that certain nutrients not only activate but also inhibit epigenetic enzymes, thereby modulating gene expression (Baek and Kim 2017)

Theriogenology 173, 93101

[DOI] [PMC free article] [PubMed] [Google Scholar] 156.Santos-Daz AI, Bizup B, Pantalen-Gmez AK, Osorio B, Barbier OC, Tzounopoulos T, et al

For instance, this group demonstrated that upon AgNPs exposure, there was upregulation of cellular metal-ion association with a significant increase in metallothionein genes that didnt induce a significant inflammatory response, indicating that AgNPs can be safely used (Fig