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But for many people, unresolved Adverse Childhood Experiences (ACEs) and chronic life stress can keep the body in a prolonged state of protection long after the original threat has passed

Mason, Selye acknowledged a major weak point in his stress theory, the failure to identify experimentally such a first mediator [293,294]

The vitamins that make up B complex are thiamine (vitamin B1), riboflavin (vitamin B2), niacin (vitamin B3), pantothenic acid (vitamin B5), pyridoxine (vitamin B6), biotin (B7), folate (B9), and cobalamin (vitamin B12)

Glycitin, purchased in powder form, was prepared to be dissolved in 1% DMSO (Zhao et al., 2023) and was given at the mentioned appropriate doses (Kazmi et al., 2020)