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Kim, Jeongseon Kim Cancers.2020
doi: 10.1016/j.tim.2011.04.002
Inhibition of the NRF2-ARE pathway abolishes the resistance to ART and GPX4 inhibitors, reversing the resistance of HNC cells to ferroptosis 56,57
Ferroptosis inducers such as erasin, in addition to iron-binding agents, have demonstrated potential in mitigating oxidative stress-induced damage and increasing cellular viability in preclinical studies (371)
