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Thrombosis and inflammation are key factors in atherosclerosis and its progression to heart attack and stroke

1c,d) and was previously suggested as a candidate for a potential activator site, first, because its positive charge might stabilize or bind GSH as GS , and, second, because of its evolutionary conserved position that is equivalent to the GSH-interacting catalytic residue of glutathione transferases 3

However, a limited number of peptides are capable of binding directly to DNA, thereby influencing fundamental biological processes at the level of gene regulation

[DOI] [PubMed] [Google Scholar] 6.Dringen R