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Serum holoTC is a better biomarker of recent B12 intake than serum B12 (or methymalonic acid or tHcy) because serum holoTC concentrations increase much faster after ingestion of B12 from a meal (i.e., 6 hours) or crystalline B12 from supplements

Using expired medication can be less effective and may even be harmful

Pregnancy and lactation: Maintaining normal vitamin B12 levels is especially important for pregnant and breastfeeding women, as low levels can affect fetal development and lead to developmental delays in breastfed babies

Vitamin B12 is a water-soluble hematopoietic vitamin occurring in meats and animal products