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Description
The Glutathione (GSH) Assay utilizes Ellmans reagent (DTNB) to measure GSH in biological samples

Glutathione plays a central role as antioxidant defense, as well as in the regulation of pathways involved in cellular homeostasis, not only as a detoxifier of endogenous and exogenous compounds, but also through its participation in processes related to cell proliferation, apoptosis, gene expression, regulation of the immune system, and metabolism of cell compounds, among others

One well-known cause is pernicious anemia
"Rejuvenation by Therapeutic Elimination of Senescent Cells"
