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[27] The connection between GSTP inhibition of the pro-apoptotic JNK pathway and the isozyme's overexpression in drug-resistant tumor cells may itself account for the tumor cells' ability to escape apoptosis mediated by drugs that are not substrates of GSTP
Maintaining healthy B12 levels helps keep homocysteine within a safe range
Linsitinib targeting IGF1R signaling may lead to promising combination therapy options for OSCC patients with DDP resistance
J Hepatol 2015;62:4219
