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At the steady state, IMs express 10-fold more arginase I than AMs, while Arg-140-fold upregulation has been detected in IMs isolated from radiation-induced lung fibrosis

They found that DDD therapeutically targets AS by enhancing mitochondrial function through the HIF-1 signaling pathway, reducing ROS levels, and modulating GPX4, Bcl2, and Bax protein levels, thereby benefiting AS and hyperlipidemia (Wu et al., 2023a)

10.1016/j.jinorgbio.2012.06.011 175 Van LaarV

After alignment, reads were filtered to include only cells with: (i) a minimum of 100 genes detected, (ii) each gene detected in a minimum of 3 cells, and (iii) cells containing 1% mitochondrial DNA