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While FOXO4 can influence mitochondrial function indirectly through its regulatory effects on cellular processes, it does not directly target mitochondria like the other mitochondria-targeted peptides listed above

[Google Scholar] 13.Pflugfelder SC
Furthermore, an inhibition of Wnt signaling during the chronic stress plays a key role in extinguishing adult hippocampal neurogenesis
doi:10.1016/0003-9861(55)90070-9
