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DOI: Published online: March 12, 2024 1 Nutrition and Foods Program, School of Family and Consumer Sciences, Texas State University, San Marcos, TX, USA 2 Institute for Translational Epidemiology & Division of Liver Diseases, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA 3 Department of Mathematics, Texas State University, San Marcos, TX, USA 4 Department of Obstetrics and Gynecology, Vagelos College of Physician and Surgeons, Columbia University, New York, NY, USA 5 Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, USA Corresponding author: Ka Kahe Department of Obstetrics and Gynecology and Department of Epidemiology, Columbia University Irving Medical Center, 622 W 168th Street, New York, NY 10032, USA E-mail: [email protected] Copyright 2024 Korean Diabetes Association This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited

Its role is especially crucial in the induction of ferroptosis, an iron-dependent cell death pathway, positioning it as a context-dependent modulator of cancer progression, neurotoxicity and neurodegeneration