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Stem Cell Biology and Regenerative Medicine, vol 69

These two events consequently disrupt the enzyme-substrate association with APP resulting in an anti-amyloidogenic effect

The dissociation constants ( K d ) measured for the dDAT constructs, used in this study, also display high-affinity interactions in the range of 2.83.8 nM for nisoxetine, similar to hNET (Supplementary Table 2)
