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Monolayer chondrocytes were infected with control adenovirus containing green fluorescence protein (Ad-GFP) or Cre recombinase virus M1 (Ad-Cre) (Vector Laboratories, Burlingame, CA, USA) at an MOI of 100 for most experiments

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The importance of peroxynitrite in mediating APAP-induced liver injury is also illustrated by the fact that direct scavenging of peroxynitrite by mitochondrial GSH49,50 or resveratrol51 also prevented protein nitration and protected against APAP-induced liver injury

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