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Description
In addition, the SLC38A2 and SLC7A5 transporters play crucial roles in Gln transport within cells

Plasmid constructions and reporter activity assay The 1200-bp DNA fragment containing the CBS promoter region from 1000 to +200 bp was amplified from SKOV3 Era-R cell genomic DNA by PCR with the following primers: CBS- Kpn I forward, 5-GGTACCGACATTTAATTCTAATTCACGTCTC-3 and CBS- Bgl II reverse, 5-AGATCTGTCCAGAGAGGGGAGCGAGTCTCGG-3

Rationale for Combination Studies Using IGF-Targeted Agents Mechanisms of Resistance The extensive interactions between the IGF axis and other signaling networks/cellular processes inevitably lead to signaling redundancy and the potential for development of primary resistance to anti-cancer therapies

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