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doi: 10.1007/s00210-007-0237-8
Additionally, thyroid hormone increased the quality of mitochondria by inducing PGC-1 and ULK1 in HepG2 cells and mouse liver tissues, which suggested the potential use of ERR agonists in metabolic illnesses through enhancing mitochondrial function [211]

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NAD+ supplementation (via NAD+, NMN, or NR) addresses the NAD+ deficit by adding more precursor substrate from outside the cell
