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Description
Single-cell genomics reveals a novel cell state during smooth muscle cell phenotypic switching and potential therapeutic targets for atherosclerosis in mouse and human

It is primerely synthesized as an acute inflammatory reactant from the liver with a molecular weight of 11685 D
this means that slightly less than 1% of the population of red cells (~200 billion cells) is replaced daily (or ~2 million per second)

The assessment of myocardial strain may also help to early detect cardiotoxicity in cancer patients (58), Ye et al
