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BCAAs can promote protein synthesis by activating mTORC1, facilitate fat oxidation by increasing the concentration of intermediates in the tricarboxylic acid cycle, and enhance the activation of S6K while inhibiting 4E-BP1 ( Some non-essential amino acids have significant effects on enhancing physical strength, and these are L-citrulline (LC), L-arginine (L-Arg), and glutamine

Through comparison between digital biomarkers retrieved by these sensors and the MFIS (completed by the patients every 4 weeks), the burden of fatigue and its worsening through social isolation could be reported

The presence of centrilobular DR may predict the progression of liver fibrosis in patients with NASH [107]

These findings suggest that early delivery of antioxidant gene therapy, such as AAV1-Sod2, could help preserve retinal function and prevent the progression of dry AMD [162]