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The stronger associations observed in childhood-onset patients suggest that early metabolic dysregulation could have lasting effects on cognitive flexibility and broader executive function
The deficiency of 25(OH)VD has been shown to cause down-regulation of alpha-1-antitrypsin expression in the lungs and emphysema in animals exposed to cigarette smoke [99]
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243,553,554 Notably, impaired regeneration due to -catenin KO in hepatocytes is eventually compensated by insulin/mTORC1 signaling activation
