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Symptoms during the first 24 hours are not diagnostic or specific and include nausea, vomiting, diaphoresis, anorexia, and lethargy, the severity of which will be in direct correlation to the size of the dose ingested

Mice with Gpx4 -deficient BM cells remained anemic with strongly elevated reticulocyte counts, whereas mice harboring Gpx4 wt/wt ;Cre ERT2 BM normalized their RBC parameters within three to six weeks (Figure 1E-H, additional RBC parameters in the Online Supplementary Figure S2B-F )