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Both NMDARs and VGCCs are concentrated on dendritic spines, mediating spine specific Ca 2+ influx
Apatinib combined with SOX (S-1+oxaliplatin) as a neoadjuvant therapy for advanced or metastatic GC also has demonstrated significant efficacy and safety and the common adverse reactions include leukopenia, neutropenia and hypertension
Depletion of Tet1 and Tet2, causes a bias towards trophectoderm differentiation in embryonic stem cells [75]
