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Another function of carnitine in human metabolism is its involvement in the detoxification process of toxic compounds (such as some foreign substances, including ampicillin, valproic acid, and salicylic acid, as well as toxic substances generated endogenously via metabolism), which are jointly excreted by the kidneys with carnitine (82)

Conditions for which this effect has been demonstrated are: glutaric aciduria II, methyl malonic aciduria, propionic acidemia, and medium chain fatty acylCoA dehydrogenase deficiency

Even though experimental and observational studies show a significant correlation between elevated levels of plasma TMAO and adverse cardiovascular events, the precise mechanism is still in place and unidentified [11]

A randomised controlledtrial comparing duloxetine and acetyl L-carnitine in fibromyalgic patients:preliminary data