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Description
found that peripheral IR (indexed by insulin AUC) was independently associated with brain iron overload (particularly in the caudate nucleus and hippocampus), and that brain iron overload was independently associated with poorer cognitive performance, suggesting that obesity and peripheral IR may impair cognition by exacerbating ironrelated pathology [84]

The N-terminal region drives GH receptor binding, IGF-1 production, and growth-promoting effects

Nature Commun 3:610.

Exploiting S-nitrosylation for cancer therapy: facts and perspectives
