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In particular, one randomized, double-blind, placebo-controlled clinical trial demonstrated that daily oral administration of equal-lower doses (5 g/day) of l-ARG for a shorter period (1 month) compared to the current study significantly increased IIEF-6 score in 34 diabetic middle-aged men affected by mildmoderate ED of unknown etiology [27]

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doi: 10.1016/j.yebeh.2012.06.016 3

Two patients had mtDNA mutations of similar pathogenicity, and four had mtDNA sequence variants of unclear pathogenicity out of 25 tested children [46]