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This type of cochlear synaptopathy, referred to as hidden hearing loss because the deficits can hide behind a normal audiogram 11 , is posited to trigger neural hyperactivity that underlies tinnitus 19,20,21 , potentially offering a valuable drug target for the development of novel tinnitus treatments

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Biological Effects of Indole-3-Propionic Acid, a Gut Microbiota-Derived Metabolite, and Its Precursor Tryptophan in Mammals Health and Disease

NBs originate from neural crest cells and typically form in the abdominal or thoracic regions in paraspinal ganglia ( MYCN is a transcription factor belonging to the highly homologous MYC -family of cellular oncogenes, ubiquitously expressed in mammals