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127 All these studies suggest that inflammatory cytokines play a major role in the production of NGF, BDNF, and neurotrophins, which results in nerve ingrowth into the disc and thus generates discogenic pain

Acknowledgements The authors would like to thank Utragenyx for their medical writing support, provided by ClinSearch (Malakoff, France)

Seven studies used electrocautery, four used triamcinolone injection, one used electrocautery and triamcinolone injection in those with recurring symptoms after electrocautery, and two studies used transurethral resection

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