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PAS staining demonstrated a reduction in the thickening of the glomerular and tubular basement membranes in the DAPA and si-Nrf2 + DAPA groups, while Masson staining indicated a decrease in collagen fiber deposition in the glomeruli and renal interstitium (Fig

doi: 10.1038/s41467-022-35264-8 63 GrayEHSrenathanUDurhamLELalnunhlimiSSteelKJACatrinaAet al

This iterative approach prevents both under-treatment and unnecessary over-treatment as conditions evolve
