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Vitamins E and C administered together in human volunteers proved effective when used prophylactically against UVB-induced epidermal damage [32]

Underlying this metabolic reprogramming is the abnormal activation of core transcription factors such as HIF-1 and NF-B, which regulate the expression of genes related to glycolysis, amino acid catabolism, and fatty acid oxidation, respectively ( Table 1 Overview of relevant metabolites and their normal functions in COPD

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Two-year long safety and efficacy of deferasirox film-coated tablets in patients with thalassemia or lower/intermediate risk MDS: phase 3 results from a subset of patients previously treated with deferasirox in the ECLIPSE study