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doi:10.1016/j.rbmo.2018.09.016
[DOI] [PMC free article] [PubMed] [Google Scholar] Ziani W
Topical application is effective for surface skin remodeling but does not replicate the systemic signaling that injectable protocols produce
It increases side effects: Higher heart rate Higher blood pressure More anxiety More insomnia When patients hit a plateau, the issue is rarely not enough medication. Its usually dietary drift or metabolic adaptation
