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Studies suggest that approximately 39% of men are affected, with prevalence increasing with ageparticularly in men over 40

Reyes, A.A., Canseco JA, Mangan J, Divi, S.N., Goyal, D.K.C., Bowles, D.R., Patel, P.D, Salmons, H.R., Morgenstern, M., Anderson, D.G., Rihn, J.A., Kurd, M.F., Hilibrand, A.S., Kepler, C.K., Vaccaro, A.R., Schroeder, G.D.: Risk Factors For Prolonged Opioid Use and Effects of Opioid Tolerance on Clinical Outcomes after ACDF Surgery

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Aging 5 (4), 622641
