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In order to restore the tissues integrity, not only do resident stem cells have to be activated, but also some differentiated cells must revert to a stem cell-like state and acquire mobility

For example, the variant of LRRK2 is a risk factor for PD in Chinese and Korean populations, corresponding to SNCA and MAPT genes in Europeans and GBA1 in Africans (Rizig et al., 2023)

and Canadian populations, namely 1.1 mg/day for adult women, 1.4 mg/day during pregnancy, and 1.6 mg/day for lactation 9 , which can be attributed to corresponding regulatory institutions that define criteria for nutritional adequacy in different ways depending on age, sex, and physiological status 10