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Description
The first step in methionine metabolism is the formation of S-adenosylmethionine (SAMe) in a reaction catalyzed by methionine adenosyltransferase (MAT) (Finkelstein, 1990

D.ShorterJ

(PubMed) Hager K, Kenklies M, McAfoose J, Engel J, Munch G
It contributes to increased levels within the body itself
