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A role for a 70-kilodaton heat shock protein in lysosomal degradation of intracellular proteins

In order to make the animal model of AFLD, all mice except control groups were gavaged a single dose of alcohol each day according to the following method: 10ml (5.14mol/L alcohol) /kg body weight in the first 4 weeks, 11ml (6.85mol/L alcohol) /kg body weight in the second 4 weeks, 12ml (8.56mol/L alcohol) /kg body weight in the final 4 weeks