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Moreover, single-nucleus RNA sequencing of postmortem ALS spinal cords identified glial populations enriched for inflammatory and activation-associated markers, many of which converge on RIPK1 signaling and necroptotic cell death pathways (Zelic et al., 2025)

Mitochondria can control the intracellular intake of iron, influencing its availability, which plays a crucial role in ferroptosis
The present review underscores the pivotal role of GSH-degrading enzymes, specifically GGT and ChaC1, in cancer development

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