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49, 649 667.doi Meister A (1995) Glutathione biosynthesis and its inhibition

Through the exosomeglialinflammation cascade, this mechanism facilitates the spread of focal neuronal injury to adjacent brain regions, thereby accelerating region-specific neurodegeneration and functional impairment in Alzheimers disease (Figure 3)

On the other hand, they reduce levels of pro-inflammatory cytokines such as TNF- and IL-6, as well as oxidative stress markers like MDA

This is part of why B12 has a strong safety record, and it is also why levels sometimes need regular replenishment during active treatment
