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These findings may help in selecting an appropriate therapeutic plans of CD5/ LNPs-FAPCAR 2.2 for IPF patients with various degrees of fibrosis in the subsequent clinical trials

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Moreover, peptides can be degraded in the oral cavity due to the variable pH of the saliva, unless supported by advanced formulation such as mucoadhesive systems, permeation enhancers, or nano-enabled delivery platforms like liposomes, niosomes and polymeric nanoparticles [66]

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