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In particular, the P301L-tau mutation is related to abnormal hyperphosphorylation of the tau protein, as well as neuronal, synaptic, and mitochondrial dysfunctions

While BM, AD, and UC-derived MSCs have all been demonstrated to express synaptophysin as evidence of the formation of a synapse 102 , AD-derived MSCs were exhibited to express the highest level of SAP-90 as compared to BM- and UC-derived MSCs, which indicates that AD-derived MSCs may be more likely to form synaptic structures 103

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(2022) used mesalazine to treat patients with large intestine damp heat-type UC as a control group and mesalazine tablets and Qingchang Huayu decoction as the research group