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Contact your GP if you experience: No improvement after 46 weeks of treatment : Whilst neurological symptoms may take longer to resolve, you should notice some improvement in energy levels or general wellbeing within this timeframe

Freezing them destroys their structure

For the AOD-9604 deep dive, see What Is AOD-9604

Unless you have a gastrointestinal condition that affects B12 absorption, it's usually not an immediate concern
