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Several neurotransmitters (serotonin, noradrenaline, dopamine, and histamine), peptides (neuromedin U, urocortin, bombesin, amylin, galanin), hormones (thyroid hormone, growth hormone) and cytokines (ciliary neurotrophic factor) also play a role in modulating feeding behavior and energy expenditure [5-10]

Although CMS is a systemic disease affecting multiple organ systems, direct mortality from this condition remains rare

Additionally, their size contributes to greater mechanical strength, lower melting points, and improved stability under physiological conditions

Data Availability Statement All of the data are contained within the article