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These results underline the ability of GrimAge V2, PhenoAge, and OMICmAge in particular, to capture signals associated with key clinical biomarkers, and add to the growing body of literature on ketamines epigenetic mechanisms and their effect on biological aging

In this study, we measured tail flick latency (TFL), arterial blood gas (ABG) chemistry, Alveolar-arterial gradient, and ventilatory parameters by whole body plethysmography to determine the responses elicited by bolus injections of fentanyl (75 g/kg, IV) in male adult SpragueDawley rats that had received a bolus injection of GSHee (100 mol/kg, IV) 15 min previously

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