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The frequency of homozygous mutant alleles (NQO1 * 2/ * 2) varies widely among different ethnic populations and has been shown to range from 4% in Caucasian to as high as 34% in the Hmong population of South East Asia (Gaedigk et al., * 2 protein displays a decreased affinity for the FAD cofactor resulting in destabilization of the NQO1 protein (Chen et al., 2014)
Makin AJ, Williams R
All analysis and ethical storage of data and specimens adhered to the University policies associated with Responsible Conduct of Research and the IRB
