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Ischemiareperfusion notably increased oxidative stress, apoptosis, and inflammatory markers, as shown by higher levels of malondialdehyde, caspase-3, TNF-, and IL-6 ( p 0.05, and homogeneity of variance using Bartletts test before the ANOVA test

In vivo pharmacokinetics, distribution and targeting affinity study Following a previously established protocol, 101,102,103,104 the pharmacokinetic profiles of USPB, USPB@SeDMSN, and USPB@SeDMSN@NM were evaluated by measuring blood iron concentrations via inductively coupled plasma mass spectrometry (ICP-MS)

Arch Surg 131(8):819-24

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